Control of cell differentiation in the cellular slime mould Dictyostelium discoideum.

نویسنده

  • J M Ashworth
چکیده

s of Communications 565th Meeting of the Biochemical Society University of Stirling 9 and 10 September 1976 CONTROL M ECH AN ISMS I N D I FFER ENTl AT1 ON AND DEVELOPMENT: a Colloquium organized by L. Stevens (Stirling) Control of Cell Differentiation in the Cellular Slime Mould Dictyostelium discoideum

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منابع مشابه

Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture.

1. A simple axenic medium suitable for the growth of the myxamoebae of a strain of the cellular slime mould Dictyostelium discoideum is described. 2. Procedures suitable for the growth of this strain in liquid and on solid media are described. 3. Conditions suitable for initiating the cell differentiation of myxamoebae grown axenically are described.

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Cell electrophoresis of the cellular slime mould Dictyostelium discoideum. I. Characterization of some of the cell surface ionogenic groups.

The reduction in cell surface charge density during the early stages of differentiation of the cellular slime mould, Dictyostelium discoideum, has been studied by the technique of cell electrophoresis. Using specific chemical reagents, it was shown that the cell surface negative charge was probably due to side chain carboxyl groups of proteins. During differentiation, there was a decrease in th...

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Cell electrophoresis of the cellular slime mould Dictyostelium discoideum. II. Relevance of the changes in cell surface charge density to cell aggregation and morphogenesis.

The reduction in the cell surface charge density of Dictyostelium discoideum during differentiation has been studied by the technique of cell electrophoresis. It was abolished under conditions in which cell aggregation was inhibited (e.g. low temperature, the presence of actinomycin D or cycloheximide). In the presence of nutrients incapable of supporting growth, cell aggregation occurred witho...

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Control of cellular differentiation by temperature in the cellular slime mould Dictyostelium discoideum.

The effects of low temperature on morphogenesis and cellular differentiation of Dictyostelium discoideum were examined. During incubation at 5 degrees C, the vegetative and preaggregation cells never developed, but cell masses at the aggregation or slug stage developed to form hemispherical, or dumbbell-shaped multicellular structures. By staining with FITC-antispore IgG, the structures formed ...

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A neutral ceramidase homologue from Dictyostelium discoideum exhibits an acidic pH optimum.

The nucleotide sequence reported for the Dictyostelium discoideum ceramidase is available on the DNA Data Bank of Japan (DDBJ). Ceramidases (CDases) are currently classified into three categories (acid, neutral and alkaline) based on their optimal pHs and primary structures. Here, we report the first exception to this rule. We cloned the CDase cDNA, consisting of 2142 nucleotides encoding 714 a...

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 4 6  شماره 

صفحات  -

تاریخ انتشار 1976